Short communication
Organic chemistry
Sadegh Rahmati; Ardeshir Khazaei; Maryam Golbaghi; Mohammad Panahimehr
Volume 6, Issue 2, pp. 109-217, Serial No. 19 , April 2018, Pages 109-113
Abstract
A convenient approach for oxidation of structurally diverse alcohols has been developed using KMnO4 as oxidant agent in the presence of a catalytic amount of Al2O3 in aqueous acetonitrile. In this method various alcohols generally afforded the corresponding carbonyl compounds directly in good to high ...
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A convenient approach for oxidation of structurally diverse alcohols has been developed using KMnO4 as oxidant agent in the presence of a catalytic amount of Al2O3 in aqueous acetonitrile. In this method various alcohols generally afforded the corresponding carbonyl compounds directly in good to high yield under ultrasound irradiation conditions. It shows that this kind of catalysis system is very active, selective and suitable for oxidation of benzylic alcohols. Furthermore, all products were obtained through a simple filtration and washed with solvent, and there was no need for column chromatography. All products have been characterized by IR and 1HNMR spectral data.
![Ultrasound assisted oxidation of various alcohols to corresponding aldehydes by using Al2O3 as catalyst](data/icc/coversheet/131486373655.png)
Original Research Article
Organic chemistry
Ajmal R Bhat
Volume 6, Issue 2, pp. 109-217, Serial No. 19 , April 2018, Pages 114-124
Abstract
Annulated pyrano[2,3-d]pyrimidine/pyrano[2,3-d]uracil derivatives were synthesized using aromatic aldehydes, active methylene compounds and barbituric acid in presence of dibutylamine (DBA) catalyst in ethanol as solvent. The different substituents on phenyl ring in the fused pyrano uracil skeleton showed ...
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Annulated pyrano[2,3-d]pyrimidine/pyrano[2,3-d]uracil derivatives were synthesized using aromatic aldehydes, active methylene compounds and barbituric acid in presence of dibutylamine (DBA) catalyst in ethanol as solvent. The different substituents on phenyl ring in the fused pyrano uracil skeleton showed productive influence on its antimicrobial activity against some gram positive and gram negative bacteria like Pseudomonas aureus, E. coli, Staphylococcus aureus, Klebsiella pneumonia and Bacillus cereus. Antibacterial screening revealed that the presence of heteroaryl, cyano and amino groups on uracil skeleton increases its penetrating power on bacterial cell wall and product becomes more biologically energetic. The antimicrobial activity results showed some definite and interesting facts about the structure activity relationship (SAR) of synthesized molecules.
![Petra, osiris and molinspiration: A computational bioinformatic platform for experimental in vitro antibacterial activity of annulated uracil derivatives](data/icc/coversheet/771522751032.png)
Original Research Article
Organic chemistry
Maryam Sojoudi; Masoud Mokhtary
Volume 6, Issue 2, pp. 109-217, Serial No. 19 , April 2018, Pages 125-133
Abstract
Water is a versatile solvent in many ways, and in this sense performing organic reactions in this medium is now of great interest. The one-pot reaction of ethyl acetoacetate or benzyl acetoacetate, with benzaldehydes and malononitrile to provide some novel 6-amino-4-aryl-5-cyano-2-methyl-4H-pyran-3-carboxylates ...
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Water is a versatile solvent in many ways, and in this sense performing organic reactions in this medium is now of great interest. The one-pot reaction of ethyl acetoacetate or benzyl acetoacetate, with benzaldehydes and malononitrile to provide some novel 6-amino-4-aryl-5-cyano-2-methyl-4H-pyran-3-carboxylates has been performed over nano MgO with high performance in water as a green solvent at 80 °C. The nanocrystalline MgO catalyst was characterized via X-ray diffraction (XRD), transmission electron microscopy (TEM) and BET analysis. This method offers considerable improvements for the synthesis of 6-amino-4-aryl-5-cyano-2-methyl-4H-pyran-3-carboxylates with concern to the yield of products, facility in operation, and green aspects without using of toxic catalysts and solvents.
![Efficient one-pot synthesis of 6-amino-4-aryl-5-cyano-2-methyl-4H-pyran-3-carboxylates catalyzed by nano MgO in water](data/icc/coversheet/261490443667.png)
Original Research Article
Organic chemistry
Mosadegh Keshavarz
Volume 6, Issue 2, pp. 109-217, Serial No. 19 , April 2018, Pages 134-142
Abstract
A facile and one-pot multicomponent synthesis of novel 1,4-disubstituted-1H-1,2,3-triazoles from alkenes at room temperature is reported. At the first step, in the presence of I2/NaN3 reagents, various alkenes were converted to the corresponding azido iodides and in the next step, the reaction of these ...
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A facile and one-pot multicomponent synthesis of novel 1,4-disubstituted-1H-1,2,3-triazoles from alkenes at room temperature is reported. At the first step, in the presence of I2/NaN3 reagents, various alkenes were converted to the corresponding azido iodides and in the next step, the reaction of these compounds with phenylacetylene in the presence of catalytic amount of sodium ascorbate/ CuSO4 afforded regioselective synthesis of 1,4-disubstituted-1H-1,2,3-triazoles in short times and at good to high yields. This greenapproach has several advantages such as short reaction times, clean reaction profiles, and simple experimental and workupprocedures. All the products were fully characterized by 1HNMR, 13CNMR, IR and CHN analysis
![One-pot multicomponent click synthesis of some novel 1,4-disubstituted-1H-1,2,3-triazoles from alkenes](data/icc/coversheet/401491194590.png)
Original Research Article
Organic chemistry
Majid Halimi; Malihe Nasrabadi
Volume 6, Issue 2, pp. 109-217, Serial No. 19 , April 2018, Pages 143-147
Abstract
The 17-membered macrocyclic spermine alkaloid protoverbine (8-phenyl-1,5,9,13-tetra azacycloheptadecan-6-one) was isolated From the aerial part of verbascum speciosum. The natural polyamines are ubiquitous bases reported to have several important functions in animals, plants and microorganisms. They ...
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The 17-membered macrocyclic spermine alkaloid protoverbine (8-phenyl-1,5,9,13-tetra azacycloheptadecan-6-one) was isolated From the aerial part of verbascum speciosum. The natural polyamines are ubiquitous bases reported to have several important functions in animals, plants and microorganisms. They are involved in processes of transcription and translation in protein synthesis and influence growth and development (cell division, differentiation, embryogenensis, etc.). In plants their involvement in organ development, flowering, fruit ripening, senescence and stress responses is reported. The structure of the protoverbine established by a study of their spectral such as 1HNMR,13C-NMR, IR, ESI-MS analyses and chemical properties. To the best of our knowledge, this is the first report of protoverbine from this species.
![Isolation and identification macrocyclic spermine alkaloid(protoverbine) from verbascum speciosum.](data/icc/coversheet/621491195245.png)
Original Research Article
Analytical chemistry
Fatemeh Sabermahani; Nosrat Madadi Mahani; Neda Pourgholamrezazadeh
Volume 6, Issue 2, pp. 109-217, Serial No. 19 , April 2018, Pages 148-159
Abstract
In this work, a low-cost activated carbon as well as non-hazardous material, with high adsorption capacity, was prepared from Melia azedarach fruit (MF) by ZnCl2 activation for the removal of Pb(II) toxic metal from aqueous solutions. The microstructure of the activated carbon was observed by Scanning ...
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In this work, a low-cost activated carbon as well as non-hazardous material, with high adsorption capacity, was prepared from Melia azedarach fruit (MF) by ZnCl2 activation for the removal of Pb(II) toxic metal from aqueous solutions. The microstructure of the activated carbon was observed by Scanning Electron Microscopy (SEM). Batch experiments have been performed as a function of pH, contact time, dose of sorbent, initial Pb(II) concentration, temperature and strength ionic. It was found that the adsorption process was very quick and the equilibrium attained within 10 min. The maximum adsorption capacity for Pb(II) using Langmuir isotherm was 111.11 mg g-1. Thermodynamic study indicated that the Pb(II) adsorption was feasible, spontaneous, and endothermic. The results show that the produced activated carbon from Melia azedarach fruit is an efficient and cost-effective adsorbent for removing Pb(II).
![Adsorption of Pb(II) by activated carbon prepared from Melia azedarach fruit: Equilibrium and thermodynamics](data/icc/coversheet/621491198385.jpg)
Original Research Article
Applied Chemistry
Liu Jiesheng; Li Faping; Xing Shanshan; He Xiang
Volume 6, Issue 2, pp. 109-217, Serial No. 19 , April 2018, Pages 160-168
Abstract
In this study, the interaction between the silica filler and polydimethylsiloxanes (PDMS) was investigated from the aspects of the bound rubber and morphological characterization. With special attention to the dynamic properties, the dynamic test was conducted by dynamic shear rheometer. The results ...
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In this study, the interaction between the silica filler and polydimethylsiloxanes (PDMS) was investigated from the aspects of the bound rubber and morphological characterization. With special attention to the dynamic properties, the dynamic test was conducted by dynamic shear rheometer. The results show that the modified fillers disperse uniformly within PDMS matrix without aggregation and connect closely with the matrix than that of the unmodified fillers. Surface modification of filler increases the bound rubber content. The increase in silica loading leads to an increase in the silica-silica interaction and a decrease in filler-rubber interaction, which results in the aggregation of fillers and the increase of the bound rubber content. It was apparent that storage modulus, loss modulus and tanδ of unvulcanized PDMS/filler compounds filled with treated silica filler were lower than that of the untreated silica system. Moreover, the tanδ decreases with increasing silica loading.
![Investigation of structural, morphological and dynamic mechanical properties of unvulcanized PDMS/silica compound](data/icc/coversheet/01522837623.png)
Original Research Article
Organic chemistry
Nahid Rasouli; Maryam Movahedi; Elaheh Aghabeikzadeh Naeini
Volume 6, Issue 2, pp. 109-217, Serial No. 19 , April 2018, Pages 169-179
Abstract
In this study, the zinc chromium ferrite magnetic nanoparticles ZnCrFeO4 are synthesized via sol-gel method and characterized by X-ray diffraction (XRD) analysis, Fourier transform infrared spectroscopy (FT-IR) and scanning electron microscopy (SEM). The XRD analysis showed that ZnCrFeO4 has single-phase ...
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In this study, the zinc chromium ferrite magnetic nanoparticles ZnCrFeO4 are synthesized via sol-gel method and characterized by X-ray diffraction (XRD) analysis, Fourier transform infrared spectroscopy (FT-IR) and scanning electron microscopy (SEM). The XRD analysis showed that ZnCrFeO4 has single-phase cubic structure. The synthesized ZnCrFeO4 has been used as an efficient catalyst for acetylation of alcohols, phenols and amines with acetic anhydride under mild and solvent free conditions. The ZnCrFeO4 catalyst can be readily removed using an external magnet and no obvious loss of activity was observed after three consecutive runs. Also, the effect of time, amount and type of catalyst were investigated.
![The zinc chromium ferrite magnetic nanoparticles ZnCrFeO4: An efficient catalyst for acetylation of alcohols, phenols and amines under solvent-free conditions](data/icc/coversheet/91491200710.png)
Original Research Article
Organic chemistry
Ali Allahresani
Volume 6, Issue 2, pp. 109-217, Serial No. 19 , April 2018, Pages 180-191
Abstract
In this study, Mn (III) salen complex was synthesized and immobilized onto the graphene oxide, which is modified by 3-chloropropyltrimethoxy silane. Heterogeneous catalyst was characterized by X-ray diffraction, transmission electron microscopy, thermogravimetric analysis, fourier transform infrared ...
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In this study, Mn (III) salen complex was synthesized and immobilized onto the graphene oxide, which is modified by 3-chloropropyltrimethoxy silane. Heterogeneous catalyst was characterized by X-ray diffraction, transmission electron microscopy, thermogravimetric analysis, fourier transform infrared spectra, nitrogen adsorption−desorption isotherm and atomic absorption spectroscopy. The catalytic activity of heterogeneous Mn (III) salen complex and comparison with its homogeneous analogue was studied for green oxidation of sulfide derivatives using aqueous 30% H2O2 as an oxidant in water media. The results showed that heterogeneous catalyst was highly efficient in this reaction and corresponding products were obtained in good to excellent yields. The advantages of this catalyst include short reaction times, no side reactions, easy and simple work up, mild reaction conditions and excellent selectivity. The heterogeneous nanocatalyst was reused for several runs without significant loss in activity and selectivity.
![Mn (III) salen complex supported on graphene oxide nanosheets as a highly selective and recoverable catalyst for the oxidation of sulfides](data/icc/coversheet/101491299557.png)
Original Research Article
Organic chemistry
Hamed Ramezanalizadeh
Volume 6, Issue 2, pp. 109-217, Serial No. 19 , April 2018, Pages 192-208
Abstract
In this work a novel heterojunction catalyst have been synthesized and employed as a highly efficient catalyst for one-pot synthesis of substituted imidazoles. Analytical methods including Fourier transform infrared (FT-IR), diffuse reflectance spectroscopy (DRS), X-ray diffraction (XRD), Energy- dispersive ...
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In this work a novel heterojunction catalyst have been synthesized and employed as a highly efficient catalyst for one-pot synthesis of substituted imidazoles. Analytical methods including Fourier transform infrared (FT-IR), diffuse reflectance spectroscopy (DRS), X-ray diffraction (XRD), Energy- dispersive X-ray spectroscopy (EDX), Scanning electron microscopy (SEM) and Vibrating Sample Magnometer (VSM) were used for the catalyst characterization. Moreover, the catalyst was also recovered and reused five times without remarkable decrease in its catalytic activity. Compared to the classical methodologies, this method illustrated significant advantages including low loading of the catalyst, short reaction times, high to excellent yields, easy separation and purification of the products.
![Design, preparation and characterization of a novel BiFeO3/CuWO4 heterojunction catalyst for one-pot synthesis of trisubstituted imidazoles](data/icc/coversheet/571491382160.png)
Original Research Article
Physical chemistry
Ahmad Razavizadeh; Fahimeh Alirezapoor
Volume 6, Issue 2, pp. 109-217, Serial No. 19 , April 2018, Pages 209-217
Abstract
In the present work, a modified equation of state has been presented for the calculation of volumetric properties of supercritical fluids. The equation of state is van der Waals basis with temperature and density-dependent parameters. This equation of state has been applied for predicting the volumetric ...
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In the present work, a modified equation of state has been presented for the calculation of volumetric properties of supercritical fluids. The equation of state is van der Waals basis with temperature and density-dependent parameters. This equation of state has been applied for predicting the volumetric properties of fluids. The densities of fluids were calculated from the new equation of state at different temperatures and pressures in the supercritical region. The predicted densities have been compared with those obtained from the experiment, over a broad range of pressure. It is found that the new equation of state yields excellent results in comparison with 1894 experimental data points with overall average absolute deviation percent (AAD %) of 0.98% in density for the pure studied compound. The studied fluids are: CH4, C2H6, C3H8, C4H10, C5H12, C6H14, C7H16, C8H18, C10H22, C12H26, C2H4, C6H6, C6H12, C7H8, O2, N2 and CO2.
![Volumetric properties of high temperature, high pressure supercritical fluids from improved van der Waals equation of state](data/icc/coversheet/91491797929.png)