Oftadeh, M., Saghaie, L., Pirialam, S. (2014). Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds. Quarterly Journal of Iranian Chemical Communication, 2(Issue 2, pp. 82-163, Serial No. 3), 82-92.
Mohsen Oftadeh; Lotfollah Saghaie; Shahla Pirialam. "Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds". Quarterly Journal of Iranian Chemical Communication, 2, Issue 2, pp. 82-163, Serial No. 3, 2014, 82-92.
Oftadeh, M., Saghaie, L., Pirialam, S. (2014). 'Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds', Quarterly Journal of Iranian Chemical Communication, 2(Issue 2, pp. 82-163, Serial No. 3), pp. 82-92.
Oftadeh, M., Saghaie, L., Pirialam, S. Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds. Quarterly Journal of Iranian Chemical Communication, 2014; 2(Issue 2, pp. 82-163, Serial No. 3): 82-92.
Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds
1Chemistry Department, Payame Noor University, 19395-4697 Tehran, Iran
2Department of Medicinal Chemistry, Faculty of Pharmacy, Isfahan University of Medical Sciences, Hezar Jerib, 81746-73461 Isfahan, I. R. of Iran.
Abstract
Today, the bidentate ligands 3-hydroxypyridin-4-ones (HPOs) as orally active iron chelating agents have been demonstrated to possess potential for treatment of some human diseases such as iron-overload in thalassaemic patients and malaria. In this research, a series of HPOs with different substitutes and position were theoretically invest
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