Document Type: Original Research Article
Authors
1 Chemistry Department, Payame Noor University, 19395-4697 Tehran, Iran
2 Department of Medicinal Chemistry, Faculty of Pharmacy, Isfahan University of Medical Sciences, Hezar Jerib, 81746-73461 Isfahan, I. R. of Iran.
Abstract
Today, the bidentate ligands 3-hydroxypyridin-4-ones (HPOs) as orally active iron chelating agents have been demonstrated to possess potential for treatment of some human diseases such as iron-overload in thalassaemic patients and malaria. In this research, a series of HPOs with different substitutes and position were theoretically invest
Graphical Abstract
 "Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds")
Keywords
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