Oftadeh, M., Saghaie, L., Pirialam, S. (2014). Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds. Iranian Chemical Communication, 2(Issue 2, pp. 82-163), 82-92.
Mohsen Oftadeh; Lotfollah Saghaie; Shahla Pirialam. "Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds". Iranian Chemical Communication, 2, Issue 2, pp. 82-163, 2014, 82-92.
Oftadeh, M., Saghaie, L., Pirialam, S. (2014). 'Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds', Iranian Chemical Communication, 2(Issue 2, pp. 82-163), pp. 82-92.
Oftadeh, M., Saghaie, L., Pirialam, S. Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds. Iranian Chemical Communication, 2014; 2(Issue 2, pp. 82-163): 82-92.
Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds
1Chemistry Department, Payame Noor University, 19395-4697 Tehran, Iran
2Department of Medicinal Chemistry, Faculty of Pharmacy, Isfahan University of Medical Sciences, Hezar Jerib, 81746-73461 Isfahan, I. R. of Iran.
Abstract
Today, the bidentate ligands 3-hydroxypyridin-4-ones (HPOs) as orally active iron chelating agents have been demonstrated to possess potential for treatment of some human diseases such as iron-overload in thalassaemic patients and malaria. In this research, a series of HPOs with different substitutes and position were theoretically invest
[12] A. Fassihi, D. Abedi, L. Saghaie, R. Sabet, H. Fazeli, G. Bostaki, O. Deilami, H. Sadinpour, Eur. J. Med. Chem., 2009, 44, 2145-2157.
[13] R.C. Hider, K. Lerch, Boichem. J., 1989, 257, 289-290.
[14] L. Saghaie, M. M. Sadeghi, A. Nikazma, Res. Pharm. Sci., 2006, 1, 40-48.
[15] H. Kubinyi, Farmaco. Sci., 1979, 34, 248–76.
[16] C. Hansch, Acct. Chem. Res., 1969, 2, 232-239.
[17] I.V. etko, J. Gasteiger, R. Todeschini, A. Mauri, D. Livingstone, P. Ertl, V.A. Palyulin, E.V. Radchenko, N.S. Zefirov, A.S. Makarenko, V.Y. Tanchuk, V.V. Prokopenkoet, J. Comput. Aid. Mol. Des., 2005, 19, 453-63.
[18] HyperChem release 7.0 for windows, copyright @ 2002, Hypercube, Inc.
[19] C. Lee, W. Yang, R.G. Parr, Phys. Rev. B, 1988, 37, 785-789.
[20] M.J. Frisch, G.W. Trucks, H.B. Schlegel, G.E. Scuseria, M.A. Robb, J.R. Cheeseman, V.G. Zakrzewski, J.A. Montgomery, R.E. Stratmann, J.C. Burant, S. Dapprich, J.M. Millam, A.D. Daniels, K.N. Kudin, M.C. Strain, O. Farkas, J. Tomasi, V. Barone, M. Cossi, R. Cammi, B. Mennucci, C. Pomelli, C. Adamo, S. Clifford, J. Ochterski, G.A. Petersson, P.Y. Ayala, Q. Cui, K. Morokuma, D.K. Malick, A.D. Rabuck, K. Raghavachari, J.B. Foresman, J. Cioslowski, J.V. Ortiz, B.B. Stefanov, G. Liu, A. Liashenko, P. Piskorz, I. Komaromi, R. Gomperts, R.L. Martin, D.J. Fox, T. Keith, M.A. Al-Laham, C.Y. Peng, A. Nanayakkara, C. Gonzalez, M. Challacombe, P. M. W. Gill, B. Johnson, W. Chen, M.W. Wong, J.L. Andres, H.G.C.M. Gonzalez, E. S. Replogle, J.A. Pople, Gaussian 98 in R.A. 6. (Ed.). Gaussian, Inc.: Pittsburgh, PA, 1998.
[21] M. W. Wong, K. Wiberg, J. Chem. Phys., 1991, 12, 8991-8998.
[22] I. Moriguchi, S. Hirono, I. Nakagome, H. Hirano, Chem. Pharm. Bull., 1994, 42, 976-978.
[23] A.K. Ghose, V.N. Viswanadhan, J.J. Wendoloski, J. Phys. Chem. A, 1998, 102, 3762-3772.
[24] L. Saghaie, R.C. Hider, S. Mostafavi, Daru., 2003, 11, 38-48.
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