@article { author = {Oftadeh, Mohsen and Saghaie, Lotfollah and Pirialam, Shahla}, title = {Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds}, journal = {Iranian chemical communication}, volume = {2}, number = {Issue 2, pp. 82-163, Serial No. 3}, pages = {82-92}, year = {2014}, publisher = {}, issn = {2423-4958}, eissn = {2345-4806}, doi = {}, abstract = {Today, the bidentate ligands 3-hydroxypyridin-4-ones (HPOs) as orally active iron chelating agents have been demonstrated to possess potential for treatment of some human diseases such as iron-overload in thalassaemic patients and malaria. In this research, a series of HPOs with different substitutes and position were theoretically invest}, keywords = {Hydroxypridinone,partition coefficient,chelating agent,density functional theory}, url = {https://icc.journals.pnu.ac.ir/article_594.html}, eprint = {https://icc.journals.pnu.ac.ir/article_594_631fbb6a231f2d821278a01bcba4d487.pdf} }