Organic chemistry
Seyyedeh Cobra Azimi; Kurosh Rad-Moghadam
Volume 3, Issue 4, pp. 283-387, Serial No. 9 , October 2015, , Pages 356-366
Abstract
A homogeneous ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate doped with LiCl ([BMIm]BF4-LiCl) was found as catalyst solvents for the synthesis of dicoumarols by the condensation of 4-hydroxycoumarin and aldehyde at 80 ˚C. In this field, several types of aromatic aldehyde, containing electron-withdrawing ...
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A homogeneous ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate doped with LiCl ([BMIm]BF4-LiCl) was found as catalyst solvents for the synthesis of dicoumarols by the condensation of 4-hydroxycoumarin and aldehyde at 80 ˚C. In this field, several types of aromatic aldehyde, containing electron-withdrawing groups as well as electron-donating groups, were rapidly changed to the corresponding derivatives in good to excellent yields. Application of this new homogeneous catalyst system offered the advantages of short reaction times, solvent-free conditions, high yields, and easy work-up procedure compared to the conventional methods of the syntheses. The ionic liquid can be recovered for the subsequent reactions and reused without any loss of efficiency.