Organic chemistry
Synthesis and characterization of new (2E,2'E)-3,3'-(((3-hydroxypropane-1,2-diyl)bis(oxy))bis (2,1-phenylene))bis(1-phenylprop-2-en-1-one) and its transformation into 2,3-bis(2-(1,3-diphenyl-4,5-dihydro-1H-pyrazol-5-yl)phenoxy)propan-1-ol

Alireza Banaei; Soheyla Karimi; Somayeh Minaei; Eslam Pourbasheer

Volume 5, Issue 1, pp. 1-120, Serial No. 14 , January 2017, , Pages 1-6

Abstract
  In this paper, new (2E, 2'E)-3, 3'-(((3- hydroxypropane-1, 2-diyl) bis (oxy)) bis (2, 1-phenylene)) bis (1-phenylprop-2-en-1-one) (2a) was prepared in good yield by condensation reaction of acetophenone with bisaldehyde (1a) in ethanolic NaOH solutions at room temperature. The (2E, 2'E)-3, 3'-(((3- hydroxypropane-1, ...  Read More

Synthesis and characterization of new (2E,2'E)-3,3'-(((3-hydroxypropane-1,2-diyl)bis(oxy))bis (2,1-phenylene))bis(1-phenylprop-2-en-1-one) and its transformation into 2,3-bis(2-(1,3-diphenyl-4,5-dihydro-1H-pyrazol-5-yl)phenoxy)propan-1-ol


Organic chemistry
A facile and efficient synthesis of Baclofen

Ali Saberi

Volume 4, Issue 2, pp. 133-235, Serial No. 11 , April 2016, , Pages 142-145

Abstract
  γ-Aminobutiric acid (GABA), the major inhibitory neurotransmitter in the central nervous system is activated by the antispastic and muscle relaxant agent, Baclofen, which is a lipophilic derivative of GABA. Because of its biological and pharmacological importance, there are several reports in the ...  Read More

A facile and efficient synthesis of Baclofen


Organic chemistry
Pharmacological properties of some 3-substituted indole derivatives, a concise overview

Kobra Nikoofar; Diba Kadivar; Samaneh Shirzadnia

Volume 2, Issue 4, pp. 236-325, Serial No. 5 , October 2014, , Pages 300-315

Abstract
  Indole is a nitrogen-containing heterocycle. It is a very important motif in agriculture and pharmacy. Many compounds containing indole moiety has been isolated form nature. It is also an important part in natural alkaloids. Tryptophan is an amino acid which posses indole. 3-Sustituted indoles are the ...  Read More

Pharmacological properties of some 3-substituted indole derivatives, a concise overview


Organic chemistry
Caesium carbonate as a highly efficient catalyst for the synthesis of macrocyclic diamides

Esmael Rostami; Maryam Bagherzadeh; Akram Khodadadi; Ay Soda Ghobadpoor; Fatemeh Dehghani; Zahra Heidari; Mahmood Feraidooni; Zahra Abshirini; Fatemeh Tavazo; Zahra Keshvarz

Volume 2, Issue 3, pp. 162-231, Serial No. 4 , July 2014, , Pages 187-195

Abstract
  In this research work, we report the synthesis of macrocyclic diamides from the reaction of diesters and aliphatic diamines in the presence of caesium carbonate. It has been demonstrated that among the carbonate of alkali metals (Li2CO3, Na2CO3, K2CO3 and CS2CO3), CS2CO3 appear to be the best catalyst ...  Read More

Caesium carbonate as a highly efficient catalyst for the synthesis of macrocyclic diamides


A practical and convenient method for the synthesis of anesthetic drug thiopental: using thiourea and sodium ethoxide

Hojat Narimani; Mostafa kazemi; Homa Kohzadi

Volume 2, Issue 1, pp. 1-81, Serial No. 2 , January 2014, , Pages 48-55

Abstract
  A general, simple, practical and convenient method has been described for the synthesis of anesthetic drug thiopental using thiourea in the presence of sodium ethoxide. Anesthetic drug of thiopental was prepared in two stages; during the first stage, the alkylation of mthyl cyanoacetate was performed ...  Read More

A practical and convenient method for the synthesis of anesthetic drug thiopental: using thiourea and sodium ethoxide