Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds

Oftadeh, Mohsen; Saghaie, Lotfollah; Pirialam, Shahla

Document Type : Original Research Article

Authors

¹ Chemistry Department, Payame Noor University, 19395-4697 Tehran, Iran

² Department of Medicinal Chemistry, Faculty of Pharmacy, Isfahan University of Medical Sciences, Hezar Jerib, 81746-73461 Isfahan, I. R. of Iran.

Abstract

Today, the bidentate ligands 3-hydroxypyridin-4-ones (HPOs) as orally active iron chelating agents have been demonstrated to possess potential for treatment of some human diseases such as iron-overload in thalassaemic patients and malaria. In this research, a series of HPOs with different substitutes and position were theoretically invest

Graphical Abstract

Keywords

References

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Iranian chemical communication

Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds

References

References

Volume 2, Issue 2, pp. 82-163, Serial No. 3
April 2014
Pages 82-92

Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds

References

References

Volume 2, Issue 2, pp. 82-163, Serial No. 3April 2014Pages 82-92

Volume 2, Issue 2, pp. 82-163, Serial No. 3
April 2014
Pages 82-92