Comparison of chelating ability of dipeptide (histidine-β-alanine) and (tetrakis(4-sulfonatophenyl)porphyrin) (TPPS4) for in vitro removal of toxic metals

Rahimi, Rahmatollah; Khosravi, Maryam; Rabbani, Mahboubeh; Safavi, Ebrahim

Document Type : Review Article

Authors

¹ Iran University of Science & Technology

² Iran University of Science and Technology

³ Member of the World Society of the Anti-Aging Medicine and International Hormone Society. Niavaran, 11977634461, Tehran, Iran.

Abstract

Peptides are one of the best candidates for drug development due to their high specificity and low toxicity and porphyrins are significant macromolecules in biological systems with important roles. In this works ynthesis of dipeptide (histidine-β-alanine) was done by solid-phase peptide synthesis method (SPPS) and tetrakis(4-sulfonatophenyl)porphyrin (TPPS4) was synthesized by Adler method. The molecular structure of the dipeptide and porphyrin was defined by using different methods such as UV-Vis, FT-IR, 1H NMR and LC-Mass spectrometry for dipeptide. Kinetics study and comparison of the chelating ability of dipeptide (histidine-β-alanine) and TPPS4 was investigated for removing of metal ions Al3+, Cu2+, Hg2+ and Pb2+ in vitro.

Graphical Abstract

Keywords

Main Subjects

Inorganic chemistry

References

[1] D. Goodwin, P. Simerska, I. Toth, Current Medicinal Chemistry, 2012, 19, 4451-61.

[2] F. Garcia-Martin, N. Bayo-Puxan, L.J. Cruz, J.C. Bohling, F. Albericio, QSAR & Combinatorial Science. 2007, 26, 1027-35.

[3] R. Rahimi, P. Hambright, J Porphyrins Phthalocyanines., 1988, 2, 493–9.

[4] A. Isidro-Llobet, M. Alvarez, F. Albericio, Chemical reviews., 2009, 109, 2455-504.

[5] F.H. Duijnhoven, R.I. Aalbers, J.P. Rovers, O.T. Terpstra, P.J. Kuppen, literaturereview. Immunobiology. 2003, 207, 105-13.

[6] H.M. Wang, J.Q. Jiang, J.H. Xiao, R.L. Gao, F.Y. Lin, X.Y. Liu, Chemico-biologicalinteractions., 2008, 172, 154-8.

[7] C.E. Brown, W.E. Antholine, Journal of Physical Chemistry, 1979, 83, 3314-9.

[8] S.P. Datta, B.R. Rabin, Short Communications, Preliminary Notes., 1956, 19, 572-4.

[9] X. Huang, K. Nakanisha, N. Berova, Chirality., 2000, 12, 237–55.

[10] B. Janssen, D. Hohenadel, P. Brinkkoetter, V. Peters, N. Rind, Diabetes., 2005, 54, 2320-7.

[11] A.A. Boldyrev, Nova Science Publisher, New York., 2006.

[12] G.D. Venosa, L. Hermida, H. Fukuda, M.V. Defain, Journal of photochemistry and photobiology B, Biology., 2009, 96, 249-54.

[13] A.R. Hipkiss, J Biochem Cell Biol., 1998, 30, 863–8.

[14] W. Ahmad, F. Shaheen, Y. Zhou, L. Zhang, Journal of Cancer Research and Experimental Oncology., 2013, 5, 8-19.

[15] S. Khoshbakht, F. Kobarfard, D. Beiki, O. Sabzevari, M. Amini, F. Mehrnejad, K. Tabib, S. Shahhosseini, J Radioanalytical Nuclear Chemistry., 2016, 307, 1125-34.

[16] E. Kaiser, R.L. Colescott, C.D. Bossinger, P.I. Cook, Analytical Biochemistry., 1970, 34, 595-8.

[17] G.B. Dolors, R. Francesc, G. Ernest, Journal of Peptide Science, 2011, 17, 32.

[18] R. Rahimi, M. Khosravi, M.H.H. Tehrani, M. Rabbani, E. Safavi, Journal of the Brazilian Chemical Society., 2016, DOI: 10.5935/0103-5053.20160064.

[19] B. Bonkowski, J. Wieczorek, M. Patel, Ch. Craig, A.L. Gravelin , T. Boncher, Modern Chemistry & Applications., 2013, 1:4.

[20] R. Rahimi, M. Jeddi, S.M.R. Ravanfar, Asian Journal of Chemistry. 2009, 21, 3988-3994.

[21] Zh. Song, A.O. Adeyemo, J. Baker, Sh.M. Traylor, M.L. Lightfoot, Georgia Journal of Science., 2011, 69, 89–101.

[22] M.L. Branham, P. Singh, K. Bisetty, M. Sabela, T. Govender, Molecules., 2011, 16, 10269-91.

Iranian chemical communication

Comparison of chelating ability of dipeptide (histidine-β-alanine) and (tetrakis(4-sulfonatophenyl)porphyrin) (TPPS4) for in vitro removal of toxic metals

References

References

Volume 6, Issue 1, pp. 1-108, Serial No. 18
January 2018
Pages 1-7

Comparison of chelating ability of dipeptide (histidine-β-alanine) and (tetrakis(4-sulfonatophenyl)porphyrin) (TPPS4) for in vitro removal of toxic metals

References

References

Volume 6, Issue 1, pp. 1-108, Serial No. 18January 2018Pages 1-7

Volume 6, Issue 1, pp. 1-108, Serial No. 18
January 2018
Pages 1-7