N,N,N,N-Tetramethylguanidinium acetate as an efficient and reusable ionic liquid catalyst for the one-pot synthesis of dihydropyrrol-2-ones

Sajadikhah, Seyed Sajad

Document Type : Original Research Article

Author

Seyed Sajad Sajadikhah

Department of Chemistry, Payame Noor University, Iran

Abstract

An extremely facile and efficient procedure which has been developed for the synthesis of dihydropyrrol-2-ones. One-pot four-component reaction of amines, dialkyl acetylenedicarboxylates and formaldehyde in the presence of N,N,N,N-tetramethylguanidinium acetate [TMG][Ac] in methanol at ambient temperature provides substituted dihydropyrrol-2-ones in good to high yields. The important aspects of this multi-component heteroannulation are simple operations under mild conditions, readily available starting material and catalyst. Furthermore, All products were obtained through a simple filtration and washed with ethanol and no need for column chromatography. It is found that the catalyst is recyclable and can be used up to four times without significant loss of its activity.

Graphical Abstract

Keywords

Main Subjects

Organic chemistry

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Iranian chemical communication

N,N,N,N-Tetramethylguanidinium acetate as an efficient and reusable ionic liquid catalyst for the one-pot synthesis of dihydropyrrol-2-ones

References

References

Volume 5, Issue 2, pp. 121-236, Serial No. 15
April 2017
Pages 121-128

N,N,N,N-Tetramethylguanidinium acetate as an efficient and reusable ionic liquid catalyst for the one-pot synthesis of dihydropyrrol-2-ones

References

References

Volume 5, Issue 2, pp. 121-236, Serial No. 15April 2017Pages 121-128

Volume 5, Issue 2, pp. 121-236, Serial No. 15
April 2017
Pages 121-128