Iranian chemical communication 2423-4958 2 Issue 4, pp. 236-325, Serial No. 5 2014 10 01 Pharmacological properties of some 3-substituted indole derivatives, a concise overview 300 315 832 EN Kobra Nikoofar chemistry department, school of sciences, alzahra university, vanak, tehran, i.t.iran Diba Kadivar Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran 1993891176, Iran Samaneh Shirzadnia Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran 1993891176, Iran Journal Article 2014 04 14 Indole is a nitrogen-containing heterocycle. It is a very important motif in agriculture and pharmacy. Many compounds containing indole moiety has been isolated form nature. It is also an important part in natural alkaloids. Tryptophan is an amino acid which posses indole. 3-Sustituted indoles are the main group of its derivatives. Because the wide-spread application of 3-substituted indolic compounds their synthetic procedures are in demand by organic chemists. In this review we have focused on about twenty compound of 3-substituted indole derivatives that showed pharmacological properties. A concise synthetic route for some of them has also been reported. The main pharmaceutical properties of these compounds are antibacterial, anticancer and antimicrobial activities. https://icc.journals.pnu.ac.ir/article_832_c7f6dcea50a9ba9c396b9f15fd5cd9ef.pdf