Organic chemistry
Mohammad Reza Poor Heravi; Aazam Monfared Monfared; Masoumeh Ahmadi
Volume 4, Issue 4, pp. 359-490, Serial No. 13 , October 2016, , Pages 433-448
Abstract
A facile and efficient synthesis of bis(indolyl)methanes derivatives (3a-u) was reported via a condensation reaction of aldehydes and indole in the presence of by silica-supported-3-(triethoxysilyl) propane-1-ammonium chloride catalysis under solvent free conditions. We studied the reaction in different ...
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A facile and efficient synthesis of bis(indolyl)methanes derivatives (3a-u) was reported via a condensation reaction of aldehydes and indole in the presence of by silica-supported-3-(triethoxysilyl) propane-1-ammonium chloride catalysis under solvent free conditions. We studied the reaction in different conditions and optimized. The use of just 0.02 g of (silica gel-ammonium salt) is sufficient. The reaction was carried out at 110 °C under thermal condition. This method, including some advantages such as mild reaction condition, easy work-up, and recoverable and reusable catalyst.A facile and efficient synthesis of bis(indolyl)methanes derivatives (3a-u) was reported via a condensation reaction of aldehydes and indole in the presence of by silica-supported-3-(triethoxysilyl) propane-1-ammonium chloride catalysis under solvent free conditions. We studied the reaction in different conditions and optimized. The use of just 0.02 g of (silica gel-ammonium salt) is sufficient. The reaction was carried out at 110 °C under thermal condition. This method, including some advantages such as mild reaction condition, easy work-up, and recoverable and reusable catalyst..
Organic chemistry
Mohammad Reza Poor Heravi; Mohammad Amirloo
Volume 3, Issue 1, pp. 1-71, Serial No.6 , January 2015, , Pages 62-71
Abstract
A simple, clean, and environmentally benign three-component process for the synthesis of 2-amino-4Hchromenes using [mim]Cl, as an efficient catalyst under solvent-free conditions are described. A wide range of aromatic aldehydes easily undergoes condensations with 1-naphthol and malononitrile under solvent-free ...
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A simple, clean, and environmentally benign three-component process for the synthesis of 2-amino-4Hchromenes using [mim]Cl, as an efficient catalyst under solvent-free conditions are described. A wide range of aromatic aldehydes easily undergoes condensations with 1-naphthol and malononitrile under solvent-free conditions to afford the desired products of good purity in excellent yields. Taking into account environmental and economical considerations, the protocol presented here has the merits of environmentally benign, simple operation, convenient work-up and good yields. Furthermore, the catalyst can be easily recovered and reused for at least five cycles without losing its activities.A simple, clean, and environmentally benign three-component process for the synthesis of 2-amino-4Hchromenes using [mim]Cl, as an efficient catalyst under solvent-free conditions are described. A wide range of aromatic aldehydes easily undergoes condensations with 1-naphthol and malononitrile under solvent-free conditions to afford the desired products of good purity in excellent yields. Taking into account environmental and economical considerations, the protocol presented here has the merits of environmentally benign, simple operation, convenient work-up and good yields. Furthermore, the catalyst can be easily recovered and reused for at least five cycles without losing its activities.
![One-pot multicomponent reaction for the synthesis of 2-amino-4-chromenes promoted by 1-methyl imidazoliumiodide [mim]Cl ionic- liquid catalyst under solvent-free conditions](data/icc/coversheet/881408343421.jpg)
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![One-pot multicomponent reaction for the synthesis of 2-amino-4-chromenes promoted by 1-methyl imidazoliumiodide [mim]Cl ionic- liquid catalyst under solvent-free conditions](javascript:loadModal('One-pot multicomponent reaction for the synthesis ... ', 'data/icc/coversheet/881408343421.jpg'))