Organic chemistry
Hamid Aliyan
Abstract
H3PW12O40 (PW12) was immobilized over mesoporous alumina through the reaction of mesoporous alumina functionalized 3-aminopropyl triethoxy silane (3-APTES) and PW12. The surface properties of the functionalized nanocomposite was analyzed by a series of characterization techniques like elemental analysis, ...
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H3PW12O40 (PW12) was immobilized over mesoporous alumina through the reaction of mesoporous alumina functionalized 3-aminopropyl triethoxy silane (3-APTES) and PW12. The surface properties of the functionalized nanocomposite was analyzed by a series of characterization techniques like elemental analysis, FTIR and XRD. XRD and adsorption–desorption analysis shows that the mesostructure of silica remains intact after various modifications, while spectral technique show the successful grafting of the neat PW12 inside the porous silica support. 3-Alkylindole derivatives were produced by ring opening of epoxides in the presence of PW12-APTES@ SBA-15 nanocomposites as an efficient catalyst. The catalyst can be reused for several times but it will be less active.
Sarvin Mohammadi-Aghdam; Hadi Jabbari; Omidali Pouralimardan; Fater Divsar; Issa Amini; Sami Sajjadifar
Abstract
In this protocol, 3-(2-carboxybenzoyl)-1-methyl-1H-imidazol-3-ium chloride [Cbmim]Cl and sulfonic acid functionalized pyridinium chloride [pyridine-SO3H]Cl as a new, reusable, and green Brønsted acidic ionic liquid (BAIL) catalyst were synthesized and successfully used for the one-pot ring opening ...
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In this protocol, 3-(2-carboxybenzoyl)-1-methyl-1H-imidazol-3-ium chloride [Cbmim]Cl and sulfonic acid functionalized pyridinium chloride [pyridine-SO3H]Cl as a new, reusable, and green Brønsted acidic ionic liquid (BAIL) catalyst were synthesized and successfully used for the one-pot ring opening of epoxide with sodium azide (NaN3) in water at room temperature. Epoxides under ring-opening easily with NaN3 in the presence of [Cbmim]Cl and [pyridine-SO3H]Cl to afford the corresponding β-azido alcohols as attractive and interesting materials in drug design and pharmaceutics compounds in high yield with good regioselective under mild reaction conditions. In this protocol, 3-(2-carboxybenzoyl)-1-methyl-1H-imidazol-3-ium chloride [Cbmim]Cl and sulfonic acid functionalized pyridinium chloride [pyridine-SO3H]Cl as a new, reusable, and green Brønsted acidic ionic liquid (BAIL) catalyst were synthesized and successfully used for the one-pot ring opening of epoxide with sodium azide (NaN3) in water at room temperature. Epoxides under ring-opening easily with NaN3 in the presence of [Cbmim]Cl and [pyridine-SO3H]Cl to afford the corresponding β-azido alcohols as attractive and interesting materials in drug design and pharmaceutics compounds in high yield with good regioselective under mild reaction conditions.
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