Biochemistry
QSAR studies and application of genetic algorithm - multiple linear regressions in prediction of novel p2x7 receptor antagonists’ activity

Alireza Banaei; Eslam Pourbasheer; Fatemeh Haggi

Volume 4, Issue 3, pp. 236-358, Serial No. 12 , July 2016, , Pages 318-336

Abstract
  Quantitative structure-activity relationship (QSAR) models were employed for prediction the activity of P2X7 receptor antagonists. A data set consisted of 50 purine derivatives was utilized in the model construction where 40 and 10 of these compounds were in the training and test sets respectively. A ...  Read More

QSAR studies and application of genetic algorithm - multiple linear regressions in prediction of novel p2x7 receptor antagonists’ activity