Iranian chemical communication2423-49584Issue 3, pp. 236-358, Serial No. 1220160701Physico-chemical features of Aqueous extract of acanthophyllum laxiusculum roots from natural steppe habitats of Iran: Evaluating surface activity and thermal behavior of partially purified extract2362442113ENHajarSoltaninejadDepartment of Energy and Environmental Biotechnology, Institute of Industrial and Environmental Biotechnology(IIEB), National Institute of Genetic Engineering and Biotechnology (NIGEB), P.O. Box 14965/161, Tehran, IranZahraMadadiDepartment of Energy and Environmental Biotechnology, Institute of Industrial and Environmental Biotechnology(IIEB), National Institute of Genetic Engineering and Biotechnology (NIGEB), P.O. Box 14965/161, Tehran, IranTayebeBagheri LotfabadDepartment of Energy and Environmental Biotechnology, Institute of Industrial and Environmental Biotechnology(IIEB), National Institute of Genetic Engineering and Biotechnology (NIGEB), P.O. Box 14965/161, Tehran, IranAtefehPiraniTraditional Medicine and Materia Medica Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.NegissaEbadipourDepartment of Energy and Environmental Biotechnology, Institute of Industrial and Environmental Biotechnology(IIEB), National Institute of Genetic Engineering and Biotechnology (NIGEB), P.O. Box 14965/161, Tehran, IranJournal Article20150520Acanthophyllum laxiusculum is one of the most widely distributed species of the genus in Iran that flourishes in steppe and mountainous regions of the country. In the present study, water-soluble content of A. laxiusculum roots was extracted by boiling water and further successively purified partially by a defined solvent system. Surface tension measurements revealed the ability of plant extract to decrease the surface tension of water from 72 to 38mN/m with a critical micelle concentration (CMC) of 87.3 mg/l. The partially purified natural extract (PPNE) exhibited 65% emulsification activity (E24) on kerosene. A combination of UV–VIS spectroscopy and Fourier transform infrared spectroscopy (FTIR) demonstrated the presence of saponin compounds in PPNE. Moreover, thermostability of PPNE was evaluated by thermal gravimetric analysis (TG) and differential thermal analysis (DTA). TG-DTG analysis showed a complex three-stage thermal degradation mechanism and this conclusion was also supported by the DTA spectrum.Iranian chemical communication2423-49584Issue 3, pp. 236-358, Serial No. 1220160701A green and eco-friendly method for the synthesis of xanthene derivatives using cellulose sulfuric acid under solvent-free conditions2452552114ENSeyyedeh CobraAzimiIslamic Azad University, Rasht, IranEsmayeelAbbaspour-GilandehIslamic Azad University, Ardabil, IranJournal Article20150913A green and convenient method for the synthesis of 14-aryl-14H-dibenzo[a,i]xanthene-8,13-diones and spiro[dibenzo[a,i]-xanthene-14,3'-indoline]-2',8,13-triones in the presence of a catalytic amount of cellulose sulfuric acid (CSA) as an efficient biopolymer-based catalyst under solvent-free conditions at 100 °C is described. The condensation reactions of β-naphtol, 2-hydroxynaphthalene-1,4-dione with aldehydes or isatins to afford the corresponding xanthenes in good to excellent yields. To the best of our knowledge, it is the first example of a multicomponent reaction to the synthesis of these compounds using cellulose sulfuric acid. The present approach offers several advantages such as shorter reaction times, simple work-up, excellent yields, non-toxicity of the catalyst, and solvent-free conditions. Moreover, cellulose sulfuric acid is successfully reused for four cycles without significant less of activity.Iranian chemical communication2423-49584Issue 3, pp. 236-358, Serial No. 1220160701Application of carbon ceramic modified electrode with prussian blue for electrocatalytic oxidation of nitrite ion2562642198ENSohrabErshadmarandNoshinSafarzadehDepartment of Chemistry, Payame Noor University, P.O. BOX 19395-4697 Tehran, IranHamzehAkhondi-YamchiDepartment of Chemistry, Payame Noor University, P.O. BOX 19395-4697 Tehran, IranJournal Article20150624A novel chemically modified electrode containing Prussian blue complex was achieved on the surface of glass carbon electrode by sol-gel technique. The electrochemical behavior of modified electrode was characterized by cyclic voltammetry in detail. The film electrode obtained was very stable and exhibited electrocatalytic response for oxidation of nitrite. Results showed at bare GC electrode, a small oxidation peak current was observed at about 740 mV and a well-formed sharp catalytic oxidation peak at about 600 mV was observed at Prussian blue complex modified electrode. The transfer coefficient (α) for electrocatalytic oxidation of nitrite and the diffusion coefficient of this substance under the experimental conditions were also investigated.Iranian chemical communication2423-49584Issue 3, pp. 236-358, Serial No. 1220160701Solid state synthesis of NiO nanoparticles from [(1,2-bis(2-formyl-3-methoxyphenyl)propane)nickel(II)] chloride2652722199ENAliakbarDehno KhalajiDepartment of Chemistry, Faculty of Science, Golestan University, Gorgan, IranFatemehGharibDepartment of Chemistry, Faculty of Science, Golestan University, Gorgan, IranJournal Article20150518In this paper, nickel oxide (NiO) nanoparticles have been prepared by solid state thermal decomposition of an acyclic nickel(II) complex (1,2-bis(2-formyl-3-methoxyphenyl)propane)nickel(II) chloride, [NiL]Cl2, in an electrical furnace at optimal temperature, 450 ºC for 3.5 h. The nickel(II) complex is obtained via solid state synthesis using nickel(II) chloride and tetradentate O4 acyclic ligand 1,2-bis(2-formyl-3-methoxyphenyl)propane. The structure and morphology of NiO nanoparticles are characterized by Fourier transform infrared spectroscopy (FT-IR), powder X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). XRD and TEM analysis show that NiO nanoparticles have pure and cubic phase with the average size of 5-10 nm.Iranian chemical communication2423-49584Issue 3, pp. 236-358, Serial No. 1220160701An efficient solvent-free synthesis of 1,8-dioxo-octahydroxanthenes by using Fe2(SO4)3.7H2O as catalyst2732822200ENReyhanehKhoeinihaDepartment of Chemistry, Faculty of Sciences, Central Tehran Branch, Islamic Azad University, P.O. BOX 14676-86831,Tehran, IranAliEzabadiDepartment of Chemistry, Faculty of Sciences, Central Tehran Branch, Islamic Azad University, P.O. BOX 14676-86831,Tehran, IranAbolfazlOlyaeiDepartment of Chemistry, Payame Noor University, PO BOX 19395-3697, Tehran, Iran.Journal Article20150901A facile and efficient protocol for the synthesis of 1,8-dioxo-octahydroxanthenes has been developed by one-pot Knoevenagel condensation, Michael addition and cyclodehydration reaction of dimedone (active methylene carbonyl compound) with aromatic aldehydes in the presence of Iron (III) sulfate hydrate as a solid acidic catalyst under solvent-free conditions. Various aromatic aldehydes were utilized in the reaction and in all situations the desired product were synthesized successfully. The present methodology is cost-effective in addition to other advantages like high yields of products in shorter reaction time and simple workup procedure. The non toxicity and easy availability of the catalyst makes this protocol efficient and environmentally benign.Iranian chemical communication2423-49584Issue 3, pp. 236-358, Serial No. 1220160701Mn(II) salen complex immobilized on nano silicagel as a recyclable heterogeneous catalyst for oxidation of alcohols to their corresponding carbonyl compounds2832942201ENMohammad AliNasseriDepartment of Chemistry, College of Sciences, University of Birjand, Birjand 97175-615, IranBatolZakerinasabDepartment of Chemistry, College of Sciences, University of Birjand, Birjand 97175-615, IranSayydeKamayestaniDepartment of Chemistry, College of Sciences, University of Birjand, Birjand 97175-615, IranJournal Article20150517Mn(II) salen complex immobilized on nano silicagel was prepared by incorporating Mn(II) salen complex into a nanosilica matrix and characterized by TGA, XRD, atomic absorption spectroscopy and was successfully applied as catalyst for the oxidation of alcohols. Oxidation of a series of alcohols in acetonitrile over immobilized Mn(II) salen complex using tetrabutylammonium peroxymonosulfate (TBAO) as oxidant were resulted to the corresponding carbonyl compounds selectively in moderate to high yields. It is noteworthy that the aldehydes do not undergo further oxdation to carboxylic acids. The yields of aromatic alcohols are higher than those of alcohols with aliphatic groups. The catalyst has been reused several times, without observable loss of its activity and selectivity.Iranian chemical communication2423-49584Issue 3, pp. 236-358, Serial No. 1220160701(Carboxy-3-oxopropylamino)-3-propylsilylcellulose as a novel organocatalyst for the synthesis of coumarin derivatives under solvent-free conditions2953082202ENMehriSalimiDepartment of Chemistry, College of Sciences, University of Birjand, P. O. Box 97175-615, Birjand, IranJournal Article20150826In this research, (Carboxy-3-oxopropylamino)-3-propylsilylcellulose (COPAPSC) as an organocatalyst, has been synthesized by grafting of succinic anhydride on the NH2-modified cellulose (cellulose functionalized with 3- aminopropyltriethoxysilane). The –CO2H group-functionalized cellulose (COPAPSC) is used as a catalyst for the synthesis of coumarin derivatives from the reaction of phenolic substrate and β- Keto-esters under solvent-free conditions. The results showed that the yield of products is between 85-94%. The advantages of this reaction include simple work-up, short reaction time, excellent yields as well as easily separation of catalyst. The catalyst can be reused several times in subsequent reactions without any decreasing in the catalyst reactivity.Iranian chemical communication2423-49584Issue 3, pp. 236-358, Serial No. 1220160701Oxidative aromatization of some 1,4-dihydropyridine derivatives using NaBrO33093172203ENMasoomehAbdoli-SenejaniAzad university of arakNilufarForuzanDepartment of chemistry, Islamic Azad university-Arak BranchMahnazBahmaniDepartment of chemistry, Islamic Azad university-Arak BranchTaherehMomeni IsfahaniDepartment of chemistry, Islamic Azad university-Arak BranchSabaDustepourDepartment of chemistry, Islamic Azad university-Arak BranchJournal Article20150923In this study, oxidation of some 3,5-diacyl or 3,5-diester 1,4-dihydropyridines to corresponding pyridine derivatives using sodium bromate in the presence of NH4Cl, NaHSO4 and Bu4NHSO4 under thermal conditions has been investigated. The yield and structure of formed products is similar under all conditions; however, the reaction is accelerated in the presence of Bu4NHSO4 and NaHSO4. In addition, oxidation of 3,5-diester 1,4-dihydropyridines, against 3,5-diacetyl 1,4-dihydropyridines using sodium bromate in the presence of tetrabutylammonium hydrogen sulfate, leads to the corresponding pyridines in shorter reaction times than sodium hydrogen sulfate. The cheapness of reagent, high yielding, easy work up and mild condition make this method a useful addition to the available methods in organic synthesisIranian chemical communication2423-49584Issue 3, pp. 236-358, Serial No. 1220160701QSAR studies and application of genetic algorithm - multiple linear regressions in prediction of novel p2x7 receptor antagonists’ activity3183362218ENAlirezaBanaeiDepartment of Chemistry, Payame Noor University (PNU), P. O. Box 19395-3697EslamPourbasheerDepartment of Chemistry, Payame Noor University (PNU), P. O. Box 19395-3697FatemehHaggiDepartment of Chemistry, Payame Noor University (PNU), P. O. Box 19395-3697, Tehran, IranJournal Article20150725Quantitative structure-activity relationship (QSAR) models were employed for prediction the activity of P2X7 receptor antagonists. A data set consisted of 50 purine derivatives was utilized in the model construction where 40 and 10 of these compounds were in the training and test sets respectively. A suitable group of calculated molecular descriptors was selected by employing stepwise multiple linear regressions (SW-MLR) and genetic algorithm-multiple linear regressions (GA-MLR) as variable selection tools. The proposed MLR models were fully confirmed applying internal and external validation techniques. The obtained results of this QSAR study showed the superiority of the GA-MLR model over the SW-MLR model. As a result, the obtained GA–MLR model could be applied as a valuable model for designing similar groups of P2X7 receptor antagonists.Iranian chemical communication2423-49584Issue 3, pp. 236-358, Serial No. 1220160701An efficient green synthesis of highly substituted imidazoles catalyzed by Al-MCM-41 nanoreactors3373462227ENAbolfazlOlyaeiDepartment of Chemistry, Payame Noor University, Qazvin, IranZohrehDerikvandbDepartment of Chemistry, Faculty of Science, Khorramabad Branch, Islamic Azad University, Khorramabad, IranFatemehNoruzianDepartment of Chemistry, Payame Noor University, PO BOX 19395-3697, Tehran, I. R. of Iran
Tel.: 0098-28-33224024; Fax number: 0098-28-33226400MahdiehSadeghpourDepartment of Chemistry, Takestan Branch, Islamic Azad University, Takestan, IranJournal Article20150930Al-MCM-41 nanoreactors is found to be a remarkable efficient catalyst for one-pot multicomponent cyclocondensation of benzil, aniline or ammonium acetate and aromatic aldehydes for the synthesis of polysubstituted imidazoles under solvent-free conditions. The reaction was efficiently promoted by 10 mg nano-Al-MCM-41 and the heterogeneous catalyst was recycled for four runs in this reaction without losing its catalytic activity. The key advantages of this process are operational simplicity, reusable catalyst, shorter reaction time, convenient work-up procedures, avoiding the use of organic solvents and purification of products by non-chromatographic methods. By this advantage, several polysubstituted imidazoles as pharmaceutical important molecules can be prepared in high yield and high purity.Iranian chemical communication2423-49584Issue 3, pp. 236-358, Serial No. 1220160701Surfactant-assisted synthesis of barium hexaferrite nanoparticles by hydrothermal method3473582229ENKamelliaNejatiDepartment of Chemistry, Payame Noor University, P.O.BOX 19395-3697 Tehran, I.R. of IranShabnamAlizadeDepartment of Chemistry, Faculty of Basic Sciences, Azarbaijan Shahid Madani University, TabrizSaraSamueyDepartment of Chemistry, Faculty of Basic Sciences, Azarbaijan Shahid Madani University, Tabriz, IranZolfagharRezvaniDepartment of Chemistry, Faculty of Basic Sciences, Azarbaijan Shahid Madani University, Tabriz, IranJournal Article20150526In the present work, the synthesis of Barium hexaferrite (BaFe12O19) nanoparticles in the<br />presence of a large excess amount of OH− anions by the hydrothermal method in the presence and absence of surfactants such as Sodium dodecyl benzene sulfonate and Triton X-114 was reported. The optimized temperature in the absence of surfactant was determined (200 °C) and then Barium hexaferrite nanoparticles were synthesized by assistance of surfactants at this temperature. In this way, it was confirmed that the secondary re-crystallization can be totally suppressed with the use of surfactant and addition of surfactant leads to the synthesis of uniform and ultrafine nanoparticles with excellent superparamagnetic properties. Barium hexaferite nanoparticles have a disc-like shape. The structure, morphology and magnetic properties of samples were characterized and investigated by Powder X-ray Diffraction (PXRD), scanning electron microscopy (SEM) and vibrating sample magnetometer (VSM) techniques.