Iranian chemical communication2423-49582Issue 2, pp. 82-163, Serial No. 320140401Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds8292594ENMohsenOftadehChemistry Department, Payame Noor University, 19395-4697 Tehran, IranLotfollahSaghaieDepartment of Medicinal Chemistry, Faculty of Pharmacy, Isfahan University of Medical Sciences, Hezar Jerib, 81746-73461 Isfahan, I. R. of Iran.ShahlaPirialamChemistry Department, Payame Noor University, 19395-4697 Tehran, IranJournal Article20131119Today, the bidentate ligands 3-hydroxypyridin-4-ones (HPOs) as orally active iron chelating agents have been demonstrated to possess potential for treatment of some human diseases such as iron-overload in thalassaemic patients and malaria. In this research, a series of HPOs with different substitutes and position were theoretically investIranian chemical communication2423-49582Issue 2, pp. 82-163, Serial No. 320140401Fabrication of new carbon paste electrodes based on gold nano-particles self-assembled to mercapto compounds as suitable ionophores for potentiometric determination of Copper ions93105605ENRasoulPourtaghavi TalemiStudentSajjadBakhtiaristudentNabiJavadistudentMortezaVatanparaststudentJournal Article20131117In the present study, we investigate the potentiometric behavior of Cu2+ carbon paste electrodes based on two mercapto compounds 2-Ethylmino-5-Mercapto-1,3,4-Thiadiazole (EAMT) and 2-Acetylamino-5-mercapto-1,3,4-thiadiazole (AAMT) self-assembled on gold nano-paricle (GNP) as ionophore. Then, the results obtained from the modified electrodes are compared. The self-assembled ionophores exhibit a high selectivity for Copper ion (Cu2+), in which the sulfur and nitrogen atoms in their structure play a role as the effective coordination donor site for the Copper ion. Among these electrodes, the best performance was obtained with the sensor with a EAMT/graphite powder/paraffin oil weight ratio of 4.0/68/28 with 200 µL of GNP exhibits the working concentration range of 1.6×10−9 to 6.3×10−2 M and a Nernstian slope of 28.9±0.4 mVdecade−1 of copper (II) activity. The detection limit of electrode was 8.9(±0.2)×10−10 M and potential response was pH independent across the range of 2.8–6.3. The proposed electrode presented very good selectivity and sensitivity towards the Cu2+ ions over a wide variety of cations including alkali, alkaline earth, transition and heavy metal ions. Also the proposed electrode was successfully applied as an indicator electrode in the potentiometric titration of Cu (II) ions with EDTA and the potentiometric determination of copper ions in spiked water samples.Iranian chemical communication2423-49582Issue 2, pp. 82-163, Serial No. 320140401Investigation of quality of storage dam ilam, identify of pollutant resources and pollutants attitude106118603ENMoayedAvazpourDepartment of Environmental Health Engineering, Ilam University of Medical Science, Ilam IranSabahShiriDepartment of Chemistry, Payam Noor University, 19395-4697 Tehran, IranFaribaSeifipourDepartment of Environmental Health Engineering, Ilam University of Medical Science, Ilam IranHeshmatollahNourmoradiDepartment of Environmental Health Engineering, Ilam University of Medical Science, Ilam IranJournal Article20131127ABSTRACT: Water quality of dam storage is highly affected by upstream environment and basin. Regarding other conducted studies, there exist various reasons such as some studies and general monitoring of dams which cause some main problems including salinity, chemical and microbial pollution eutrophication, and sedimentation. Chame-Gardalan Storage Dam in Ilam Province is one of the storages which have many environmental issues because of discharge upstream rural wastewaters, animal excreta, agricultural drainage, and leachate. The aim of this study is to signify the quality of Ilam’s storage Dam and also to recognize the pollutant resources and to analyze the pollutants’ behavior at different times and sites in order to determine dam properties for agricultural and domestic usages. Regarding the importance of the topic, the present study (in the year 2012) is based on the collected information of water quality of the basin, recognition of pollutant resources and measurement of qualitative parameters such as Temperature, TDS, EC, BOD5, COD, nitrogen, phosphor, and pH in seven periods of time (from May to November). The results show that the total increase in the concentration of all variables along the basin are over double, in particular, Nitrat, Sulfat, BOD, and COD. After analyzing data with some water quality indexes, we analyzed water quality of the storage and some strategies were applied in order to control of effect decrease in the dam storage which, a management program was presented to improve water quality.Iranian chemical communication2423-49582Issue 2, pp. 82-163, Serial No. 320140401Trace determination and separation of tin (II) by floatation-spectrophotometric using kalmagyte and CTAB119128604ENSabahShiriDepartment of Chemistry, Payam Noor University, 19395-4697 Tehran, IranMoaydAvazpourDepartment of Environmental Health Engineering, Ilam University of Medical Science, Ilam IranAliDelpishehDepartment of Epidemiology, Ilam University of Medical Science, Ilam, IranMaryamLoeimydDepartment of Food Hygiene, Faculty of Veterinary Medicine,Shahid Chamran University of Ahvaz,IranJournal Article20131130ABSTRACT<br />A novel floatation-spectrophotometric extraction method was developed for the recovery of tin (II) from aqueous samples prior to determination by UV spectrophotometric detection. The method is based on the formation of a complex between tin (II) and kalmagyte in pH=8. The complex is floated in the interface of n-hexane and aqueous phases. After removing the aqueous phase, the floated particles are dissolved in methanol and the absorbance is measured at 637 nm. Different parameters of the floatation-spectrophotometric technique such as reagent concentration, pH, surfactant, standing time and interfering ions were studied and optimized to obtain the best extraction results with the minimum interference from other compounds. Under these conditions, the extraction of the target compound was almost complete (mean values of recovery was more than 92.6%) in a short time (6 min). The optimized method demonstrated good linearity (r2 > 0.9991) in the range of 4-350 ng/mL, sensitivity (limit of detection for tin (II), 1.7 ng/mL), accuracy (0.19–7.35%) and precision (3.66%, 4.21%). The applicability of the proposed method was demonstrated by extraction of tin(II) from different water samples.Iranian chemical communication2423-49582Issue 2, pp. 82-163, Serial No. 320140401Synthesis and characterization of novel silyl derivatives of curcumin129136625ENMehdiNabatiAzarbaijan Shahid Madani UniversityMehrdadMahkamAzarbaijan Shahid Madani UniversityJournal Article20131231Abstract:<br />Turmeric is a member of the ginger family (Zingiberaceae), which is extensively used as a spice, food preservative and colouring material. Curcumin is a main bioactive natural compound derived from the rhizome of this plant. Curcumin can exist in several tautomeric forms, keto and enol. The keto form is more stable than enol form. Silyl ethers have proven to be versatile substrates for a wide variety of organic reactions and they are prepared by reacting an alcohol and a silicon halide using a base such as triethylamine in stoichiometric quantity. Curcumin silyl ether derivatives were prepared under mild conditions. The stability of products decreases with increasing size of the silyl substitutions and the products will be unstable.Iranian chemical communication2423-49582Issue 2, pp. 82-163, Serial No. 320140401The SAMP-/RAMP -hydrazone methodology in asymmetric synthesis of 4S-ferrugineone and 4S, 5S-ferrugineol: The pheromones of palm weevils137146633ENHamidSaeidianDepartment of Science, Payame Noor University (PNU), PO Box: 19395-4697, Tehran, IranDieterEndersInstitute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074, Aachen, GermanyZohrehMirjafaryDepartment of Chemistry, Science and Research Branch Islamic Azad University, Tehran, IranJournal Article201401224S-ferrugineone and 4S,5S-ferrugineol as pheromones of palm weevils were synthesized in 3 and 4 steps, respectively, starting from nonane-5-one employing SAMP-/RAMP -hydrazone methodology. 5-nonanone is transformed to its corresponding RAMP hydrazone by reaction with the enantiomerically pure hydrazine RAMP. Metalation with lithium diisopropylamide (LDA) in ether to form azaenolate, followed by methylation with methyl iodide, furnishes the product hydrazone. Finally, cleavage of the hydrazone moiety to regenerate the carbonyl functionality is possible by ozonolysis, leads to the 4S-ferrugineone. The crucial step would be the final diastereoselective reduction to the 4S, 5S-ferrugineol.The 4S, 5S-ferrugineol has been obtained with better yield (71%) and good disteromeric excess 40% de at -78 °C.Iranian chemical communication2423-49582Issue 2, pp. 82-163, Serial No. 320140401pKa predictions of some aniline derivatives by ab initio calculations147156665ENRezaBehjatmaneshPayame Noor UniversityNeginSafaeianDepartment of Chemistry, Payame Noor University, 19395-4697 Tehran, IranJournal Article20131224: In this work, different levels of theory containing HF, B3LYP, and MP2 with different basis sets such as 6-31G, 6-31G*, 6-311G, 6-311+G, 6-31+G*, 6-31+G are used to predict relative acidity constants of some aniline derivatives. Three different kinds of radii containing UAHF, Bondi, and Pauling are used to study how cavity forms change acidity constants. In all cases, DPCM model is used to simulate solvation Gibbs free energy. Furthermore, one similar level and basis set has been linked to IEFPCM and DPCM models to compare the results. To relate gas-phase Gibbs free energy to the solution Gibbs free energy, a simple thermodynamic cycle is used. Results show that quantum chemical calculations are robust techniques for estimating acidity constants.Iranian chemical communication2423-49582Issue 2, pp. 82-163, Serial No. 320140401Efficient classical synthesis of aminoazines under microwave irradiation157163666ENSeyed MohammadVahdatDepartment of Chemistry, Ayatollah Amoli Branch, Islamic Azad University, P.O. Box 678, Amol, IranAbbasMohammadzadehChemistry Research Laboratory, Faculty of Science,Ayatollah Amoli Branch, Islamic Azad University, Amol, IranEsmaielDerafshianDepartment of Chemistry, Ayatollah Amoli Branch, Islamic Azad University, P.O. Box 678, Amol, IranSomaiehAkhoondiDepartment of Chemistry, Ayatollah Amoli Branch, Islamic Azad University, P.O. Box 678, Amol, IranJournal Article20140115In the present study, Aminoazines were prepared from the reaction of amidrazone hydroiodide with various aromatic aldehydes in the presence of a solid base under microwave irradiation with power level of 850 W for 2-7 min in high yields. The amidrazone hydroiodide can also be prepared by the reaction of S-methyl isothiobenzamide hydroiodide and hydrazine in methanol under nitrogen gas. All synthesized compounds were characterized on the basis of IR and 1H NMR spectral data. The significant features of this method are short reaction times, high yields of the products, solvent free reaction, easy work-up procedure, directly production of aminoazines.