Iranian chemical communication
2423-4958
2345-4806
2
Issue 2, pp. 82-163, Serial No. 3
2014
04
01
Theoretical evaluation of medicinal properties for some of N-aryl-3-hydroxypyridine-4-ones derivative compounds
82
92
EN
Mohsen
Oftadeh
Chemistry Department, Payame Noor University, 19395-4697 Tehran, Iran
m_oftadeh@pnu.ac.ir
Lotfollah
Saghaie
Department of Medicinal Chemistry, Faculty of Pharmacy, Isfahan University of Medical Sciences, Hezar Jerib, 81746-73461 Isfahan, I. R. of Iran.
saghaie@pharm.mui.ac.ir
Shahla
Pirialam
Chemistry Department, Payame Noor University, 19395-4697 Tehran, Iran
sh.pirialam@gmail.com
Today, the bidentate ligands 3-hydroxypyridin-4-ones (HPOs) as orally active iron chelating agents have been demonstrated to possess potential for treatment of some human diseases such as iron-overload in thalassaemic patients and malaria. In this research, a series of HPOs with different substitutes and position were theoretically invest
Hydroxypridinone,partition coefficient,chelating agent,density functional theory
https://icc.journals.pnu.ac.ir/article_594.html
https://icc.journals.pnu.ac.ir/article_594_631fbb6a231f2d821278a01bcba4d487.pdf
Iranian chemical communication
2423-4958
2345-4806
2
Issue 2, pp. 82-163, Serial No. 3
2014
04
01
Fabrication of new carbon paste electrodes based on gold nano-particles self-assembled to mercapto compounds as suitable ionophores for potentiometric determination of Copper ions
93
105
EN
Rasoul
Pourtaghavi Talemi
Student
rasoulpourtaghavitalemi@yahoo.com
Sajjad
Bakhtiari
student
sajjadbakhtiari@yahoo.com
Nabi
Javadi
student
nabi250@gmail.com
Morteza
Vatanparast
student
mvatanparast@yahoo.com
In the present study, we investigate the potentiometric behavior of Cu2+ carbon paste electrodes based on two mercapto compounds 2-Ethylmino-5-Mercapto-1,3,4-Thiadiazole (EAMT) and 2-Acetylamino-5-mercapto-1,3,4-thiadiazole (AAMT) self-assembled on gold nano-paricle (GNP) as ionophore. Then, the results obtained from the modified electrodes are compared. The self-assembled ionophores exhibit a high selectivity for Copper ion (Cu2+), in which the sulfur and nitrogen atoms in their structure play a role as the effective coordination donor site for the Copper ion. Among these electrodes, the best performance was obtained with the sensor with a EAMT/graphite powder/paraffin oil weight ratio of 4.0/68/28 with 200 µL of GNP exhibits the working concentration range of 1.6×10−9 to 6.3×10−2 M and a Nernstian slope of 28.9±0.4 mVdecade−1 of copper (II) activity. The detection limit of electrode was 8.9(±0.2)×10−10 M and potential response was pH independent across the range of 2.8–6.3. The proposed electrode presented very good selectivity and sensitivity towards the Cu2+ ions over a wide variety of cations including alkali, alkaline earth, transition and heavy metal ions. Also the proposed electrode was successfully applied as an indicator electrode in the potentiometric titration of Cu (II) ions with EDTA and the potentiometric determination of copper ions in spiked water samples.
Gold nano-particle,Self-assembly,Potentiometric determination,Carbon Paste Electrode,Copper ions
https://icc.journals.pnu.ac.ir/article_605.html
https://icc.journals.pnu.ac.ir/article_605_86708f5ef73f222d2920a119d5f11510.pdf
Iranian chemical communication
2423-4958
2345-4806
2
Issue 2, pp. 82-163, Serial No. 3
2014
04
01
Investigation of quality of storage dam ilam, identify of pollutant resources and pollutants attitude
106
118
EN
Moayed
Avazpour
Department of Environmental Health Engineering, Ilam University of Medical Science, Ilam Iran
m_f_1859@yahoo.com
Sabah
Shiri
Department of Chemistry, Payam Noor University, 19395-4697 Tehran, Iran
sabahshiri5@yahoo.com
Fariba
Seifipour
Department of Environmental Health Engineering, Ilam University of Medical Science, Ilam Iran
fseifipour@gmail.com
Heshmatollah
Nourmoradi
Department of Environmental Health Engineering, Ilam University of Medical Science, Ilam Iran
ilam_nourmoradi@yahoo.com
ABSTRACT: Water quality of dam storage is highly affected by upstream environment and basin. Regarding other conducted studies, there exist various reasons such as some studies and general monitoring of dams which cause some main problems including salinity, chemical and microbial pollution eutrophication, and sedimentation. Chame-Gardalan Storage Dam in Ilam Province is one of the storages which have many environmental issues because of discharge upstream rural wastewaters, animal excreta, agricultural drainage, and leachate. The aim of this study is to signify the quality of Ilam’s storage Dam and also to recognize the pollutant resources and to analyze the pollutants’ behavior at different times and sites in order to determine dam properties for agricultural and domestic usages. Regarding the importance of the topic, the present study (in the year 2012) is based on the collected information of water quality of the basin, recognition of pollutant resources and measurement of qualitative parameters such as Temperature, TDS, EC, BOD5, COD, nitrogen, phosphor, and pH in seven periods of time (from May to November). The results show that the total increase in the concentration of all variables along the basin are over double, in particular, Nitrat, Sulfat, BOD, and COD. After analyzing data with some water quality indexes, we analyzed water quality of the storage and some strategies were applied in order to control of effect decrease in the dam storage which, a management program was presented to improve water quality.
Ilam Dam,Basin,pollutant resources,BOD,COD
https://icc.journals.pnu.ac.ir/article_603.html
https://icc.journals.pnu.ac.ir/article_603_737bac4ff1fd8de31cca391374117b6a.pdf
Iranian chemical communication
2423-4958
2345-4806
2
Issue 2, pp. 82-163, Serial No. 3
2014
04
01
Trace determination and separation of tin (II) by floatation-spectrophotometric using kalmagyte and CTAB
119
128
EN
Sabah
Shiri
Department of Chemistry, Payam Noor University, 19395-4697 Tehran, Iran
sabahshiri5@yahoo.com
Moayd
Avazpour
Department of Environmental Health Engineering, Ilam University of Medical Science, Ilam Iran
m_f_1859@yahoo.com
Ali
Delpisheh
Department of Epidemiology, Ilam University of Medical Science, Ilam, Iran
alidelpisheh@yahoo.com
Maryam
Loeimyd
Department of Food Hygiene, Faculty of Veterinary Medicine,Shahid Chamran University of Ahvaz,Iran
maryamloveimy@yahoo.com
ABSTRACT<br />A novel floatation-spectrophotometric extraction method was developed for the recovery of tin (II) from aqueous samples prior to determination by UV spectrophotometric detection. The method is based on the formation of a complex between tin (II) and kalmagyte in pH=8. The complex is floated in the interface of n-hexane and aqueous phases. After removing the aqueous phase, the floated particles are dissolved in methanol and the absorbance is measured at 637 nm. Different parameters of the floatation-spectrophotometric technique such as reagent concentration, pH, surfactant, standing time and interfering ions were studied and optimized to obtain the best extraction results with the minimum interference from other compounds. Under these conditions, the extraction of the target compound was almost complete (mean values of recovery was more than 92.6%) in a short time (6 min). The optimized method demonstrated good linearity (r2 > 0.9991) in the range of 4-350 ng/mL, sensitivity (limit of detection for tin (II), 1.7 ng/mL), accuracy (0.19–7.35%) and precision (3.66%, 4.21%). The applicability of the proposed method was demonstrated by extraction of tin(II) from different water samples.
floatation-spectrophotometric,tin (II),kalmagyte,Water Samples
https://icc.journals.pnu.ac.ir/article_604.html
https://icc.journals.pnu.ac.ir/article_604_b431a8800b79922607715414124ce1ae.pdf
Iranian chemical communication
2423-4958
2345-4806
2
Issue 2, pp. 82-163, Serial No. 3
2014
04
01
Synthesis and characterization of novel silyl derivatives of curcumin
129
136
EN
Mehdi
Nabati
Azarbaijan Shahid Madani University
mnabati@ymail.com
Mehrdad
Mahkam
Azarbaijan Shahid Madani University
mehdi_1046@yahoo.com
Abstract:<br />Turmeric is a member of the ginger family (Zingiberaceae), which is extensively used as a spice, food preservative and colouring material. Curcumin is a main bioactive natural compound derived from the rhizome of this plant. Curcumin can exist in several tautomeric forms, keto and enol. The keto form is more stable than enol form. Silyl ethers have proven to be versatile substrates for a wide variety of organic reactions and they are prepared by reacting an alcohol and a silicon halide using a base such as triethylamine in stoichiometric quantity. Curcumin silyl ether derivatives were prepared under mild conditions. The stability of products decreases with increasing size of the silyl substitutions and the products will be unstable.
Keywords: turmeric,Curcuma Longa,curcumin,silyl ethers,silicon halide
https://icc.journals.pnu.ac.ir/article_625.html
https://icc.journals.pnu.ac.ir/article_625_f726499dda70a815a126b236ea5821c1.pdf
Iranian chemical communication
2423-4958
2345-4806
2
Issue 2, pp. 82-163, Serial No. 3
2014
04
01
The SAMP-/RAMP -hydrazone methodology in asymmetric synthesis of 4S-ferrugineone and 4S, 5S-ferrugineol: The pheromones of palm weevils
137
146
EN
Hamid
Saeidian
Department of Science, Payame Noor University (PNU), PO Box: 19395-4697, Tehran, Iran
saeidian1980@gmail.com
Dieter
Enders
Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074, Aachen, Germany
saeidian@iran.ir
Zohreh
Mirjafary
Department of Chemistry, Science and Research Branch Islamic Azad University, Tehran, Iran
zmirgafary@yahoo.com
4S-ferrugineone and 4S,5S-ferrugineol as pheromones of palm weevils were synthesized in 3 and 4 steps, respectively, starting from nonane-5-one employing SAMP-/RAMP -hydrazone methodology. 5-nonanone is transformed to its corresponding RAMP hydrazone by reaction with the enantiomerically pure hydrazine RAMP. Metalation with lithium diisopropylamide (LDA) in ether to form azaenolate, followed by methylation with methyl iodide, furnishes the product hydrazone. Finally, cleavage of the hydrazone moiety to regenerate the carbonyl functionality is possible by ozonolysis, leads to the 4S-ferrugineone. The crucial step would be the final diastereoselective reduction to the 4S, 5S-ferrugineol.The 4S, 5S-ferrugineol has been obtained with better yield (71%) and good disteromeric excess 40% de at -78 °C.
Pheromone,4S-ferrugineone,4S,5S-ferrugineol,SAMP/RAMP hydrazone
https://icc.journals.pnu.ac.ir/article_633.html
https://icc.journals.pnu.ac.ir/article_633_86fc41f61b2bb633c0edef3911876eb4.pdf
Iranian chemical communication
2423-4958
2345-4806
2
Issue 2, pp. 82-163, Serial No. 3
2014
04
01
pKa predictions of some aniline derivatives by ab initio calculations
147
156
EN
Reza
Behjatmanesh
Payame Noor University
reza_b_m_a@yahoo.com
Negin
Safaeian
Department of Chemistry, Payame Noor University, 19395-4697 Tehran, Iran
behjatmanesh@pnu.ac.ir
: In this work, different levels of theory containing HF, B3LYP, and MP2 with different basis sets such as 6-31G, 6-31G*, 6-311G, 6-311+G, 6-31+G*, 6-31+G are used to predict relative acidity constants of some aniline derivatives. Three different kinds of radii containing UAHF, Bondi, and Pauling are used to study how cavity forms change acidity constants. In all cases, DPCM model is used to simulate solvation Gibbs free energy. Furthermore, one similar level and basis set has been linked to IEFPCM and DPCM models to compare the results. To relate gas-phase Gibbs free energy to the solution Gibbs free energy, a simple thermodynamic cycle is used. Results show that quantum chemical calculations are robust techniques for estimating acidity constants.
Ab initio,aniline,acidity constant,pKa,DFT
https://icc.journals.pnu.ac.ir/article_665.html
https://icc.journals.pnu.ac.ir/article_665_a4bd2413ebf7ad3fd5071531dc43de7f.pdf
Iranian chemical communication
2423-4958
2345-4806
2
Issue 2, pp. 82-163, Serial No. 3
2014
04
01
Efficient classical synthesis of aminoazines under microwave irradiation
157
163
EN
Seyed Mohammad
Vahdat
Department of Chemistry, Ayatollah Amoli Branch, Islamic Azad University, P.O. Box 678, Amol, Iran
vahdat_mohammad@yahoo.com
Abbas
Mohammadzadeh
Chemistry Research Laboratory, Faculty of Science,Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
abbasm633@yahoo.com
Esmaiel
Derafshian
Department of Chemistry, Ayatollah Amoli Branch, Islamic Azad University, P.O. Box 678, Amol, Iran
s.derafshian@chmail.ir
Somaieh
Akhoondi
Department of Chemistry, Ayatollah Amoli Branch, Islamic Azad University, P.O. Box 678, Amol, Iran
sayeh473@yahoo.com
In the present study, Aminoazines were prepared from the reaction of amidrazone hydroiodide with various aromatic aldehydes in the presence of a solid base under microwave irradiation with power level of 850 W for 2-7 min in high yields. The amidrazone hydroiodide can also be prepared by the reaction of S-methyl isothiobenzamide hydroiodide and hydrazine in methanol under nitrogen gas. All synthesized compounds were characterized on the basis of IR and 1H NMR spectral data. The significant features of this method are short reaction times, high yields of the products, solvent free reaction, easy work-up procedure, directly production of aminoazines.
Aminoazine,aldehyde,microwave irradiation
https://icc.journals.pnu.ac.ir/article_666.html
https://icc.journals.pnu.ac.ir/article_666_9aeaea39104de5c60dee69251ee42838.pdf