%0 Journal Article %T A green and eco-friendly method for the synthesis of xanthene derivatives using cellulose sulfuric acid under solvent-free conditions %J Iranian chemical communication %I %Z 2423-4958 %A Azimi, Seyyedeh Cobra %A Abbaspour-Gilandeh, Esmayeel %D 2016 %\ 07/01/2016 %V 4 %N Issue 3, pp. 236-358, Serial No. 12 %P 245-255 %! A green and eco-friendly method for the synthesis of xanthene derivatives using cellulose sulfuric acid under solvent-free conditions %K Xanthenes %K cellulose sulfuric acid %K 2-hydroxynaphthalene-1,4-dione %K β-naphtol %K solvent-free %R %X A green and convenient method for the synthesis of 14-aryl-14H-dibenzo[a,i]xanthene-8,13-diones and spiro[dibenzo[a,i]-xanthene-14,3'-indoline]-2',8,13-triones in the presence of a catalytic amount of cellulose sulfuric acid (CSA) as an efficient biopolymer-based catalyst under solvent-free conditions at 100 °C is described. The condensation reactions of β-naphtol, 2-hydroxynaphthalene-1,4-dione with aldehydes or isatins to afford the corresponding xanthenes in good to excellent yields. To the best of our knowledge, it is the first example of a multicomponent reaction to the synthesis of these compounds using cellulose sulfuric acid. The present approach offers several advantages such as shorter reaction times, simple work-up, excellent yields, non-toxicity of the catalyst, and solvent-free conditions. Moreover, cellulose sulfuric acid is successfully reused for four cycles without significant less of activity. %U https://icc.journals.pnu.ac.ir/article_2114_a646e9fc09ce4c04ee20060cdc661819.pdf