Organic chemistry
Design, synthesis and anticancer evaluation of novel thiazine, pyrimidine and pyridine derivatives

Amira A. Ghoneim; Mohamed G. Assy; Enaiat K. Mohamed; Islam Ragab

Volume 5, Issue 2, pp. 121-236, Serial No. 15 , April 2017, , Pages 195-206

Abstract
  Acylisothiocyanate (1) was allowed to react with benzylidene malononitrile producing oxazine derivative (2). Also, compound (1) was reacted with sodium azide followed by refluxing with sodium ethoxide affording thiazinotetrazole derivative (4). The reaction of acetylacetone with compound (1) gave pyridine ...  Read More

Design, synthesis and anticancer evaluation of novel thiazine, pyrimidine and pyridine derivatives